NF-kappa-B inhibitor beta (NFKBIB) Peptide
Quick Overview for NF-kappa-B inhibitor beta (NFKBIB) Peptide (ABIN980677)
Target
Origin
Source
Application
-
-
Characteristics
- This is a synthetic peptide designed for use in combination with anti-NFKBIB antibody (Catalog #: ARP34505_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
Purification
- Purified
-
-
-
-
Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Concentration
- 1 mg/mL
-
Buffer
- Final peptide concentration is 1 mg/mL in PBS.
-
Handling Advice
- Avoid repeated freeze-thaw cycles.
-
Storage
- -20 °C
-
Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- NFKBIB (NF-kappa-B inhibitor beta (NFKBIB))
-
Background
-
Inhibition of NFkappa-B activity by the hepatitis C virus core protein might be related to its physical interaction with and interrupted nuclear localization of IKKbeta. Increased nuclear factor-kappaB (NF-kB) activity in the amnion during labor is associated with an increase in the expression of NF-kBp65 and of the NF-kB binding proteins IkBa, IkBb-1 and IkBb-2. IkappaBbeta may be a novel target for transcription factors of the HMG-box SRY/Sox family and imply a potential role for NF-kappaB/IkappaBbeta in spermatogenesis.
Alias Symbols: IKBB, TRIP9
Protein Interaction Partner: IKBKB,MCC,RELA,RELA,BTRC,CD3EAP,CHUK,CUL1,IKBKB,IKBKG,KPNA2,LRPPRC,MCC,MTIF2,NFKB1,NFKB2,NFKBIA,NGFR,NKIRAS1,NKIRAS2,PDCD2,POLR1A,POLR1B,POLR1C,POLR1D,POLR1E,POLR2H,POLR2L,RASAL2,REL,RELA,RXRA,SKP1,BTRC,CHUK,IKBKB,NKIRAS1,REL,RELA,RXRA,Thrb
Protein Size: 356 -
Molecular Weight
- 38 kDa
-
Gene ID
- 4793
-
NCBI Accession
- NM_002503, NP_002494
-
UniProt
- Q15653
Target
-